Welcome to Anzilotti Orthodontics!

It is our pleasure to welcome you to Anzilotti Orthodontics, the office of Dr. Clifford Anzilotti, Sr. and Dr. Clifford Anzilotti, Jr.  With offices in Wilmington and Middletown, Delaware, we provide exceptional orthodontic care and courteous service for patients of all ages in a caring and comfortable environment.

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Our doctors and their staff love creating beautiful smiles! We offer a wide range of treatment options including invisible ceramic braces, Invisalign Teen and Invisalign clear aligners. Our office is equipped with the latest technology such as digital imaging and advanced computer graphics.

We recognize that every patient has different needs and lifestyles, and we pride ourselves in providing you with the personalized and professional orthodontic care you come to expect and deserve. Our top priority is to help you achieve and maintain a beautiful, healthy smile that will last a lifetime!

Contact us today to schedule your appointment!

Two Convenient Locations

Wilmington Offce

2101 Foulk Rd.
Wilmington, DE 19810

Phone: (302) 475-2050

Middletown Office

112 St. Anne's Church Rd.
Middletown, DE 19709

Phone: (302) 378-2778

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Update 6/30/20 Our Wilmington office is without power, which affects the phone system. If you call and don't get an answering machine, we apologize. Please call back in the morning and we will be happy to take care of you. Thanks for your patience.

We are seeing patients, but still on a limited capacity.  We appreciate your patience as we continue to expand the opening of the practice.  Please call (302) 475-2050 to schedule an appointment.
NEW: we are having trouble accessing requests for appointments via the website portal. Please call the office if you are requesting an appointment.
We will be available for emergencies. Please call the office at (302) 475-2050 for an emergency appointment. If you are not sure if your situation is an emergency, please feel free to call. The doctor can determine if you need to be seen.
Any changes in office procedures will be posted on this website. We miss our patients, and hope you are well. 



We have been an Invisalign Preferred Provider since 2002! The Invisalign System is a series of clear aligners that have been generated by computer simulation to gradually move the teeth. Learn More...

Invisalign Teen

Invisalign Teen

Invisalign Teen is the perfect teeth-straightening system for today’s teens’ busy lifestyles! It is the clear way to straighten teeth without metal braces, using custom-made removable aligners.
Learn More

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We are proud to be a continuing sponsor of the

Delaware Mud Run, Jr.


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