Welcome to Anzilotti Orthodontics!

It is our pleasure to welcome you to Anzilotti Orthodontics, the office of Dr. Clifford Anzilotti, Sr. and Dr. Clifford Anzilotti, Jr.  With offices in Wilmington and Middletown, Delaware, we provide exceptional orthodontic care and courteous service for patients of all ages in a caring and comfortable environment.

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Our doctors and their staff love creating beautiful smiles! We offer a wide range of treatment options including invisible ceramic braces, Invisalign Teen and Invisalign clear aligners. Our office is equipped with the latest technology such as digital imaging and advanced computer graphics.

We recognize that every patient has different needs and lifestyles, and we pride ourselves in providing you with the personalized and professional orthodontic care you come to expect and deserve. Our top priority is to help you achieve and maintain a beautiful, healthy smile that will last a lifetime!

Contact us today to schedule your appointment!

Two Convenient Locations

Wilmington Offce

2101 Foulk Rd.
Wilmington, DE 19810

Phone: (302) 475-2050

Middletown Office

112 St. Anne's Church Rd.
Middletown, DE 19709

Phone: (302) 378-2778

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Update as of  Tuesday 3/31/20
We are not seeing scheduled appointments at this time.  Thanks for your patience and understanding. 
We will be available for emergencies. Please call the office at (302) 475-2050 for an emergency appointment. 
Any changes will be posted on this website. Please see the letter below for more information.

Dear Patients, Families and Friends,

With the COVID-19 crisis upon us, we wanted to let you know that the health and safety of our patients, families and staff is our #1 concern. Like you, we are watching and listening to the health experts as well as our local emergency management agencies. We are all in this together, and changes can occur daily. We are attempting to keep you updated.


If you are sick with a fever, a cough, or if you just feel unwell, we ask that you reschedule the appointment. We need to consider the health of our staff and our patients.


We are asking patients to come to the appointment with one adult only. Please do not bring siblings to the appointments. This will allow adequate space between people in our waiting rooms. If you need to wait in the car, one of our staff will be happy to walk your child out to the car at the end of the appointment.


We also ask that patients brush their teeth before coming to the appointment. Removing the need to use the toothbrush area will reduce the risk of contamination. If you forget, that’s ok. Please know that we are sanitizing solid surfaces often.


Please know, we will always be available for emergencies.


If you have any questions or concerns, please don’t hesitate to contact the office.



We have been an Invisalign Preferred Provider since 2002! The Invisalign System is a series of clear aligners that have been generated by computer simulation to gradually move the teeth. Learn More...

Invisalign Teen

Invisalign Teen

Invisalign Teen is the perfect teeth-straightening system for today’s teens’ busy lifestyles! It is the clear way to straighten teeth without metal braces, using custom-made removable aligners.
Learn More

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We are proud to be a continuing sponsor of the

Delaware Mud Run, Jr.


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